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所有的雌性哺乳动物,如果在胎儿发育时期受到异常量的雄激素与雌激素作用,将影响其成年后卵巢的功能。胎儿时期仅雄激素不足,对卵巢发育几乎无影响;但雌激素不足将导致卵母细胞和卵泡发育受损,使其成年后卵巢发育不成熟或发育异常,胎儿时期受到过多的雌激素或雄激素的作用都会导致其成年后相似的卵巢功能低下,发生类似多囊卵巢综合征的症状:表现为增大的多个卵泡,雄激素过多症,伴随黄体生成激素(LH)分泌过多的卵巢不排卵,卵母细胞发育能力降低。
All female mammals, if subjected to abnormal amounts of androgens and estrogens during fetal development, will affect ovarian function in their adult life. Only the lack of androgen during the fetal period, almost no effect on ovarian development; However, lack of estrogen will lead to oocyte and follicular development is impaired, so that the adult ovary immature or dysplasia, fetus during excessive estrogen or Androgenic effects can lead to similar ovarian dysfunction in adulthood, with symptoms similar to polycystic ovary syndrome: increased follicles, hyperandrogenism, with excessive secretion of luteinizing hormone (LH) The ovary does not ovulate, oocyte development ability is reduced.