心房肽Atriopeptin是由心房肌特殊颗粒分泌的新激素。它的主要作用是利尿、利钠、扩张血管和降低血压。目前研究心房肽的主要方法是放射免疫分析法和免疫组织化学分析法。制备灵敏度高、特异性强的心房肽抗血清,是这两种方法必不可少的条件。我们采用人工合成的α—人心房利钠尿多肽(Alpha-Human Atrial Natriuretic Polypeptide,α-hANP) Atriopeptin is a new hormone secreted by special granules of atrial muscle. Its main role is diuretic, sodium, dilation of blood vessels and lower blood pressure. The current main method for studying atrial natriuretic peptide is radioimmunoassay and immunohistochemistry. Preparation of high sensitivity and specificity of atrial natriuretic peptide antiserum is an indispensable condition for both methods. We used artificial synthesis of α-atrial natriuretic peptide (Alpha-Human Atrial Natriuretic Polypeptide, α-hANP)