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本文报道给家兔静脉注射高分子右旋糖酐制作球结膜和软脑膜微循环障碍的动物实验模型,观察了粘多糖制剂脑心舒对球结膜和软脑膜微循环障碍的作用以及脑组织形态学和超微结构的改变。资料表明脑心舒能改善微循环障碍,加快血流速度,解聚聚集的红细胞,减轻微小动脉痉挛,增加毛细血管开放数,保护血管内皮细胞,减轻脑水肿和出血,阻止纤维样蛋白在毛细血管中的沉积。
This article reports an animal model of intravenous injection of high molecular weight dextran to rabbits to produce microcirculatory disturbances of the conjunctiva and pia mater, and observes the effect of the glucopolysaccharide preparation Naoxinshu on the microcirculatory disturbance of the bulbar conjunctiva and pia mater, and the morphological and ultrastructural changes of the brain. Microstructure changes. Data show that Naoshushu can improve microcirculatory disturbances, accelerate blood flow velocity, deaggregate aggregated red blood cells, reduce microarterial spasm, increase capillary opening, protect endothelial cells, reduce brain edema and hemorrhage, and prevent fibrillar protein in the capillaries Deposition in blood vessels.