本文报道20例活动性柯兴病经蝶骨显微外科手术探查后的外科、病理及内分泌的研究结果。自1974年2月～1976年10月,对20例柯兴病患者(男3例,女17例)进行了经蝶骨显微外科蝶鞍探查,平均年龄32.8(7～62)岁,其中1例在7年前放射治疗不佳,二例分别在4、10年前作双侧肾上腺切除,但都复发了柯兴病。20例病人决定作垂体探查完全是 This paper reports the surgical, pathological, and endocrine findings of 20 patients with active Cushing’s disease after transsphenoidal microsurgery. From February 1974 to October 1976, 20 patients with Cushing’s disease (3 males and 17 females) underwent transsphenoidal microsurgery sella exploration with an average age of 32.8 (7 to 62) years. One case had poor radiotherapy 7 years ago, and two cases had bilateral adrenalectomy four or ten years ago, but all had Cushing’s disease relapsed. 20 patients decided to do pituitary exploration is entirely