肺泡气氧分压低可以引起肺血管收缩、肺动脉压升高、甚至肺心病。然而肺动脉高压和肺心病往往不与肺通气障碍或肺泡气氧分压下降的程度呈平行关系。这是因为肺血管对缺氧的反应不仅取决于肺泡缺氧的程度,还与肺血管本身的反应性等机体内在因 Alveolar oxygen partial pressure can cause pulmonary vasoconstriction, pulmonary hypertension, and even pulmonary heart disease. However, pulmonary hypertension and pulmonary heart disease often do not have a parallel relationship with the degree of pulmonary ventilatory disturbances or alveolar pneumoconiosis. This is because the pulmonary vascular response to hypoxia depends not only on the degree of alveolar hypoxia, but also with the pulmonary vascular reactivity and other intrinsic causes