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早在1969年Flowers等就在Circulation上撰文描述了QRS波群的顿挫、切迹等QRS波碎裂(文中称之为高频成分),指出在既往心肌梗死以及左右心室扩大的患者中并不少见。嗣后Friedman(1975年)、Gardner(1985年)分别发表了基于犬心肌梗死模型动物实验的研究结果,指出这些碎裂的QRS波是由心肌瘢痕导致的缓慢、非均匀传导所致。1982年Wiener在Circulation撰文
As early as 1969, Flowers et al. Wrote an article on Circulation describing QRS complex constriction, notch and other QRS wave fragmentation (referred to herein as high frequency components), noting that in patients with previous myocardial infarction and left and right ventricular enlargement Rare. Subsequently, Friedman (1975) and Gardner (1985) published the results of animal studies based on canine myocardial infarction models, respectively, indicating that these fragmented QRS waves are caused by the slow, non-uniform conduction of myocardial scarring. Written by Wiener in Circulation in 1982