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目的分析广州市海珠区手足口病的流行特征,探索相应的防制策略和措施。方法对广州市海珠区2008年手足口病病例进行流行病学调查分析;依据卫生部颁发的《手足口病实验室检测方案试行2008版》采用RT-PCR技术检测肠道病毒。结果2008年海珠区共报告手足口病643例,男性404例,女性239例,男女性别比为1.69∶1,病例年龄以0～6岁为主,占93.94%(604/643);5月为发病高峰,占病例总数的68.12%。采集临床诊断病例的粪便标本95份,检出肠道病毒阳性39份(EV71 5份,CoxA16 23份,其他肠道病毒11份)。结论广州市海珠区2008年手足口病病例以0～6岁儿童为主,托幼儿童和外来流动人口儿童是手足口病防控的重点人群。
Objective To analyze the epidemic characteristics of hand, foot and mouth disease in Haizhu District, Guangzhou City, and to explore the corresponding prevention and control strategies and measures. Methods Epidemiological investigation of HFMD cases in Haizhu District of Guangzhou in 2008 was conducted. RT-PCR was used to detect enterovirus according to the “Hand-Foot-and-Mouth Disease Laboratory Test Plan for 2008” issued by the Ministry of Health. Results A total of 643 HFMD cases were reported in Haizhu District in 2008, including 404 males and 239 females, with a sex ratio of 1.69:1. The age of cases was 0 ~ 6 years old, accounting for 93.94% (604/643) The peak incidence, accounting for 68.12% of the total number of cases. A total of 95 stool samples were collected from clinically diagnosed cases and 39 positive enterovirus (EV71, 23 CoxA16 and 11 other enteroviruses) were detected. Conclusion The cases of hand-foot-mouth disease in Haizhu District of Guangzhou are mainly children aged 0-6 years. Children of kindergarten and migrant children are the key population of hand-foot-mouth disease prevention and control.