众所周知,慢性阻塞性肺疾病是一种常伴随有显著肺外表现的慢性炎症性疾病,心血管疾病风险增加即此类肺外表现之一。慢性阻塞性肺疾病与心血管疾病之间相关机制复杂,吸烟、衰老、缺氧、全身性炎症、氧化应激及用药等多种因素均可能参与其中。现就其潜在关联机制的研究现状予以综述。 It is well known that chronic obstructive pulmonary disease is a chronic inflammatory disease that often accompanies significant extrapulmonary manifestations. One of the extrapulmonary manifestations is the increased risk of cardiovascular disease. The related mechanisms between chronic obstructive pulmonary disease and cardiovascular diseases are complex, and many factors such as smoking, aging, hypoxia, systemic inflammation, oxidative stress and medication may be involved. The current research on its underlying mechanisms is reviewed.