肝纤维化是各种慢性肝病向肝硬化发展的必经阶段,是一切慢性肝病的共同病理基础,不同病因导致肝纤维化共同途径是肝星状细胞的激活,转化为肌成纤维细胞,合成大量的细胞外基质(ECM),ECM分泌增加,降解减少,以致其在肝内大量沉积,肝纤维化逐渐形成。故肝星状细胞活化是肝纤维化发? Liver fibrosis is a necessary stage for the development of various chronic liver diseases toward liver cirrhosis and is the common pathological basis for all chronic liver diseases. The common pathways leading to liver fibrosis by different causes are activation of hepatic stellate cells, conversion into myofibroblasts, synthesis A large number of extracellular matrix (ECM), ECM secretion increased, reduced degradation, resulting in a large number of deposition in the liver, liver fibrosis gradually formed. So hepatic stellate cell activation is fibrosis?