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目前认为自身免疫反应造成的肝脏损害是慢性活动性肝炎的主要发病机理。免疫抑制剂对控制自身免疫反应所致的肝脏损害疗效尚不肯定,多数学者对皮质激素治疗慢性活动性肝病持否定态度。目前还没有根治慢性乙型肝炎的有效药物。从作者对益气中药多年的实验研究,发现保元汤对细胞免疫功能有双向调整作用,能促进巨噬细胞舌噬作用及网状内皮系统清除率;体外T淋巴细胞培养时,高浓度保元汤明显抑制T淋巴细胞在有丝分裂作用下DNA合成,低浓度有促进T淋巴细胞增殖作用。
It is currently believed that liver damage caused by autoimmune reactions is the main pathogenesis of chronic active hepatitis. The efficacy of immunosuppressive agents in controlling liver damage caused by autoimmune reactions is not yet certain, and most scholars hold a negative attitude toward corticosteroid treatment of chronic active liver disease. There is currently no effective drug for eradicating chronic hepatitis B. From the author’s many years of experimental research on Yiqi Chinese herbal medicine, it was found that Baoyuantang has two-way adjustment of cellular immune function, can promote macrophage lingual phagocytosis and reticuloendothelial system clearance; in vitro T lymphocyte culture, high concentration of protection Yuan Tang significantly inhibited the synthesis of DNA by T lymphocytes under mitosis, and low concentrations promoted the proliferation of T lymphocytes.