论文部分内容阅读
目的:探讨淋巴母细胞淋巴瘤(LBL)临床病理及免疫学特征。方法:对18例LBL的临床、细胞形态学、免疫表型以及其对治疗、预后的影响进行了分析。结果:18例中骨髓浸润14例,淋巴瘤白血病10例,纵隔肿物9例。病理曲核细胞型15例,均为T细胞标记。全组完全缓解6例,3例B细胞型均完全缓解。18例患者中位存活期10.1个月,5年生存率11.2％。结论:LBL男性多见,发病年龄轻,易累及骨髓、纵隔。曲核、T细胞型为主。治疗反应差,生存期短,但B细胞型LBL预后相对较佳。
Objective: To investigate the clinicopathological and immunological characteristics of lymphoblastoma lymphoma (LBL). Methods: The clinical, cytomorphological and immunophenotypes of 18 cases of LBL were analyzed, and their effects on treatment and prognosis were analyzed. Results: Of the 18 cases, 14 cases were bone marrow infiltration, 10 cases were lymphoma leukemia, and 9 cases were mediastinal tumors. Pathological nucleus cell type in 15 cases, all T cell markers. Six patients were completely relieved in the whole group, and all three cases had complete remission. The median survival time of 18 patients was 10.1 months, and the 5-year survival rate was 11.2%. Conclusion: LBL males are more common, and the age of onset is light, and it is easy to affect bone marrow and mediastinum. Quercus, T cell type. The treatment response is poor and the survival period is short, but the prognosis of B-cell type LBL is relatively better.