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作者在国内首次建立一株能用于制备人源性单克隆抗体(McAb)的人鼠种间骨髓瘤细胞系FMC1(Human-mouse Heteromyeloma FMC—1)。FMC—1对8-偶氮鸟嘌呤(8-Azaguanine)及乌本苷(Ouabaine)具有抵抗性,最大耐受剂量分别达64ng/ml和1×10~(-4)M;对HAT(Hy-
For the first time in China, the authors established a human-mouse Heteromyeloma FMC-1 human-mouse interstitial myeloma cell line that can be used to prepare human monoclonal antibodies (McAbs). FMC-1 was resistant to 8-Azaguanine and Ouabaine, and the maximum tolerated dose was 64ng / ml and 1 × 10 -4 M respectively. To HAT (Hy -