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目的 :比较国产和进口阿莫西林 克拉维酸治疗小儿细菌性肺炎的临床疗效。方法 :随机选择住院的肺炎病儿 4 0例 ,分为治疗组 (男性 11例 ,女性 9例 ,年龄 2 7mo±s 12mo)和对照组 (男性 12例 ,女性 8例 ,年龄 2 9mo± 16mo)。分别选用国产及进口阿莫西林 克拉维酸 ,剂量均为 30mg·kg- 1,iv ,gtt ,bid ,疗程 10~ 14d。结果 :治疗组总有效率为 80 % ,对照组总有效率为 90 % ,2组的疗效比较经Ridit分析差异无显著意义 (P >0 .0 5 ) ,2组均未见不良反应。结论 :国产阿莫西林 克拉维酸与进口阿莫西林 克拉维酸临床疗效相似。
Objective: To compare the clinical efficacy of domestic and imported amoxicillin clavulanic acid in the treatment of pediatric bacterial pneumonia. Methods: Forty patients with pneumonia were randomly selected and divided into treatment group (11 males, 9 females, age 2 7mo ± s 12mo) and control group (12 males, 8 females, age 29 months ± 16 months ). Domestic and imported amoxicillin clavulanic acid were selected, the dose was 30mg · kg-1, iv, gtt, bid, treatment 10 ~ 14d. Results: The total effective rate was 80% in the treatment group and 90% in the control group. There was no significant difference in the curative effect between the two groups by Ridit analysis (P> 0.05). No adverse reactions were found in the two groups. Conclusion: The clinical efficacy of domestic amoxicillin clavulanic acid and imported amoxicillin clavulanic acid are similar.