Kiedrowski M等人为了评价患者性别、年龄、家族史以及结直肠远端肿瘤作为结直肠近端晚期肿瘤形成(癌或晚期腺瘤)的危险因素的影响,对从2000~2004年在华沙地区通过结肠镜检查筛选出的10 111例研究对象用多元逻辑回归模型进行了分析。为了提高研究的可比性,研究者把近端结肠定义为结肠左曲(133例)或降结肠和乙状结肠间的弯曲部(167例)。研究发现,在两种定义的小组中,各自都至少有1例存在晚期肿瘤病灶;分别有11例和14例发生癌变;在130例和163例中至 Kiedrowski M, et al. To evaluate the impact of patient gender, age, family history, and the risk of colorectal distal neoplasia as a late-stage colorectal neoplasia (cancer or advanced adenoma), Kiedrowski M et al. A total of 10 111 subjects screened by colonoscopy were analyzed using multivariate logistic regression models. To improve the comparability of the study, the researchers defined the proximal colon as the left colon (133 cases) or between the descending colon and sigmoid colon (167 cases). The study found that at least one of the two defined groups had advanced tumor lesions, 11 and 14, respectively, and in 130 and 163