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小细胞肺癌(SCLC)常发生骨髓转移。作者回顾分析了1980年1月～1986年12月行骨髓活检和抽吸检查的129例 SCLC 的资料,骨髓受侵者占总数30%,骨髓作为唯一转移部位者仅3例(2.3%)。作者比较了有骨髓转移与无骨髓转移两组患者的乳酸脱氢酶、谷草转氮酶、谷丙转氨酶、碱性磷酸酶、血清白蛋白、血清钠等6项生化指标。其中单项谷草转氨酶能正确地区分出78%的骨髓受累病例;骨髓病性贫血也是骨髓受累的重要指示,在25例骨髓病
Small cell lung cancer (SCLC) often occurs in bone marrow metastasis. The authors retrospectively reviewed data from 129 SCLC patients who underwent bone marrow biopsy and aspiration between January 1980 and December 1986, with 30% of patients with bone marrow involvement and only 3 patients (2.3%) with only bone marrow as the only metastatic site. The authors compared six biochemical markers of lactate dehydrogenase, aspartate transaminase, alanine aminotransferase, alkaline phosphatase, serum albumin, serum sodium in patients with and without bone marrow metastasis. In which single aspartate aminotransferase can correctly distinguish 78% of cases of bone marrow involvement; bone marrow anemia is also an important indicator of bone marrow involvement in 25 cases of bone marrow disease