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目的初步分析川东北地区居民食管癌发病的危险因素。方法采用以医院为基础的1∶1配对病例对照研究方法,对90例食管癌新发病例及90例与之在年龄、性别和居住地相匹配的非患癌对象进行面对面问卷调查。采用非条件Logistic回归分析法对所获得的调查资料进行统计学分析。结果既往食管病史(OR=5.000)、不按时就餐(OR=3.454)、喜食硬食(OR=4.784)、进食快(OR=3.515)、喜食泡菜(OR=5.938)和喜食蔬菜(OR=0.358)与食管癌发病存在相关性(P<0.05)。结论既往食管病史、不按时就餐、喜食硬食、进食快和喜食泡菜可能是食管癌发病的危险因素,喜食蔬菜可能降低食管癌的发病风险。
Objective To analyze the risk factors of esophageal cancer among residents in northeastern Sichuan. Methods A hospital-based 1: 1 matched case-control study was conducted to investigate 90 newly diagnosed cases of esophageal cancer and 90 non-cancer patients matched with their age, sex and residence by face-to-face questionnaire. Unconditional logistic regression analysis was used to make statistical analysis of the survey data obtained. Results The history of esophageal cancer (OR = 5.000), fasting (OR = 3.454), eating hard meals (OR = 4.784), fasting (OR = 3.515), eating kimchi (OR = 5.938) and eating vegetables OR = 0.358) was associated with the incidence of esophageal cancer (P <0.05). Conclusions The previous history of esophageal cancer, not eating on time, eating hard food, eating fast and eating kimchi may be the risk factors of esophageal cancer, eating vegetables may reduce the risk of esophageal cancer.