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目的探讨经皮胆红素测定(TCB)与微量血总胆红素测定在新生儿高胆红素血症中的疗效。方法随机选取80例新生儿(孕龄32~40周),在入院时和光疗(4次)后同时行TCB及微量血血清总胆红素测定并分析两者的相关性。结果入院时及前2次光疗后TCB与微量血血清总胆红素测定两者之间无明显差异(均P<0.05),但后2次光疗后TCB与微量血总胆红素测定两者之间存在差异性(P>0.05)。结论 TCB测定方便、快捷、准确,对诊断、动态监测早期高胆红素血症具有较好的临床应用价值,但中后期微量血总胆红素测定更准确。
Objective To investigate the efficacy of transdermal bilirubin assay (TCB) and trace amount of total bilirubin in neonatal hyperbilirubinemia. Methods Totally 80 newborns (gestational age from 32 to 40 weeks) were randomly selected. TCB and trace serum total bilirubin were measured at admission and after phototherapy (4 times), and their correlation was analyzed. Results There was no significant difference between TCB and micro-serum total bilirubin (P <0.05) both at the time of admission and before the second phototherapy, but both TCB and micro-total bilirubin There was a difference between the two groups (P> 0.05). Conclusion The determination of TCB is convenient, rapid and accurate. It has a good clinical value in the diagnosis and dynamic monitoring of early hyperbilirubinemia. However, the determination of total bilirubin in micro-blood in the later period is more accurate.