化脓性脑膜炎为儿童时期常見之疾患;但新生儿期此病比較少見。天津医科大学附属医院小儿科自1948年1月至1957年12月共收容化脓性脑膜炎患者154例,其中四例为新生儿,占化脓性脑膜炎之2.6％。現将此四例报告于后。第一例孙×,住院号31145,8天,男孩。于1952年11月8日因发烧二日,三小时来抽风数次而自产科婴儿室轉入儿科病房。自二日前起发烧,不規则,最高39.4℃,食慾減退,未吐。入儿科病房前三小时起有抽风,发作頻繁,每次1—2分钟即好。当时查体呈重病容,前囟凸出。面部皮肤有細小出血点,頸软,心肺腹无异常发現。臍带已脫落,局部无炎状。布氏征及克氏征均阴性。当时白血球总数为12250,中性多形核占69％。作腰椎穿刺,脊脑液为淡绿色脓性,镜下检查均为脓細胞,塗片发现革兰氏阴性桿菌,糖5管阴性,潘氏試驗强阳性。住院期间实驗室检查:白細胞12700—28400,中性多形核56—82％。脊脑液为淡黄绿色脓性,白细胞1274—5800。99％以上为多形核細胞,潘氏試 Purulent meningitis is a common childhood disease; but neonatal disease is relatively rare. Pediatrics of Affiliated Hospital of Tianjin Medical University from January 1948 to December 1957 were housed in 154 cases of purulent meningitis, of which four cases of neonates, accounting for 2.6% of purulent meningitis. Now report the four cases later. The first case of Sun ×, hospitalization 31145,8 days, boy. On November 8, 1952, he was admitted to the pediatric ward from the obstetric baby room for several episodes of fever on the second and third hours. Since the two days ago, fever, irregular, the highest 39.4 ℃, loss of appetite, did not spit. Into the pediatric ward three hours before the ventilation, frequent seizures, each 1-2 minutes is good. At that time, the examination showed severe illness, protruding front balsam. Facial skin has a small bleeding point, neck soft, no abnormal heart-lung found. Umbilical cord has been off, no inflammation of the local. Brinell sign and Keshi sign were negative. At that time the total number of white blood cells was 12250, 69% of neutral polymorphonuclear. For lumbar puncture, light green duodenal fluid purulent, microscopic examination were pus cells smear found Gram-negative bacilli, sugar 5 tube negative, strong positive PAN test. Laboratory tests during hospitalization: white blood cells 12700-28400, 56-82% of neutral polymorphisms. Spinal fluid is yellowish green purulent, leukocytes 1274-5800.99% for polymorphonuclear cells, Pan test