果糖在器官移植中，是许多器官保存液的重要组成成分之一，国外有实验表明：果糖可能保护缺氧肝细胞，并减少缺氧肝细胞的死亡［１］。本研究通过缺氧离体灌流小鼠肝脏进行观察，以期获得果糖对缺氧肝损保护作用的可靠实验依据。１　材料与方法１．１　动物　选用本校实验动物 Fructose in organ transplantation is one of the important components of many organ preservation solution. Experiments abroad show that fructose may protect hypoxic liver cells and reduce the death of hypoxic hepatocytes [1]. In this study, we observed the liver of mice perfused with hypoxia in order to obtain a reliable experimental basis for the protective effect of fructose on hypoxic liver damage. 1 Materials and Methods 1.1 animal selection of our laboratory animals