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目的 应用临床常用指标,预测良性前列腺增生(BPH)发生急性尿潴留(AUR)的几率。方法回顾78名BPH患者病史,分为曾发生AUR(A组)28例,从未发生AUR(B组)50例。分别比较两组间在前列腺总体积(PV)、前列腺移行区体积(TZV)、移行区指数(TZI)和前列腺特异抗原(PSA)、游离前列腺特异抗原(F-PSA)、游离与总前列腺特异抗原比值(F/T-PSA)等指标上的差异性,寻找其中能用于预测AUR的临床指标。应用ROC曲线即受试者工作特性曲线,确定相关指标预测AUR的分界值。结果 A组平均PV、TZV和PSA值皆明显高于B组,上述3个指标在A、B两组间存在显著性差异。而A、B两组在年龄、TZI、F-PSA、F/T-PSA上都无显著性差异。在预测AUR方面PSA可能比前列腺体积指标更具临床价值。结论可通过PV、TZV及PSA来预测BPH中AUR的发生。根据不同临床需要确定预测AUR的临界值,有利于及早对BPH高危人群进行监控和治疗干预。
Objective To predict the incidence of acute urinary retention (AUR) in patients with benign prostatic hyperplasia (BPH) by using common clinical indexes. Methods A retrospective review of 78 patients with BPH was divided into 28 cases of AUR (A group) and 50 cases of AUR (B group). Total prostate volume (TZV), transition zone index (TZI), prostate specific antigen (PSA), free prostate specific antigen (F-PSA), free and total prostate specific Antigen ratio (F / T-PSA) and other indicators of the differences, looking for which can be used to predict the clinical indicators of AUR. The ROC curve is used to test the working characteristic curve of the subject to determine the cutoff value of the related index prediction AUR. Results The average PV, TZV and PSA values in group A were significantly higher than those in group B. The above three indexes were significantly different between groups A and B. There was no significant difference in age, TZI, F-PSA and F / T-PSA between A and B groups. PSA may be more clinically valuable than Prostatic Volume Index in predicting AUR. Conclusions The occurrence of AUR in BPH can be predicted by PV, TZV and PSA. According to different clinical needs to determine the critical value of predicting AUR, is conducive to early monitoring and treatment of high-risk BPH populations intervention.