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上呼吸道肿瘤多见于喉和咽部,但梭形细胞癌则少见。此肿瘤以往曾被命名为假性肉瘤、多形性癌、癌肉瘤等。它们大都反映了对组织类型和梭形细胞来源的不同解释。近年来电镜的应用,对梭形细胞肿瘤的认识有了很大进展。不少喉和咽部的鳞状细胞癌,可转变为梭形细胞癌,但其它部位的梭形细胞癌多源于中胚层。作者在704例患者中,大多以光镜检查为基础进行确诊,同时愈来愈多的使用了电镜。本文目的在于提醒注意对喉的梭形细胞癌与结缔组织肿瘤的可能混淆及二者鉴别的可能性。举例如下。
Upper respiratory tract tumors are more common in the throat and pharynx, but spindle cell carcinoma is rare. This tumor has been named as pseudosurgery, pleomorphic carcinoma, carcinosarcoma, etc. in the past. Most of them reflect different interpretations of the type of tissue and the origin of spindle cells. In recent years, the use of call mirrors has made great progress in the understanding of spindle cell tumors. Many squamous cell carcinomas of the larynx and pharynx can be transformed into spindle cell carcinomas, but spindle cell carcinomas of other sites mostly originate from the mesoderm. Of the 704 patients, the authors mostly diagnosed on the basis of light microscopy. At the same time, more and more electron microscopy was used. The purpose of this article is to draw attention to the possible confusion between the spindle cell carcinoma of the larynx and connective tissue tumors and the possibility of their identification. Examples are as follows.