本文对有关化合物进行了毒性、诱变性和DNA 损伤的测试,结果简要列于下表。毒性是以细胞存活率的下降表示;诱变性是以一定剂量范围内对6-硫鸟嘌呤的抗性来衡量,在此范围内可使90C的细胞丧失活力。 The compounds were tested for toxicity, mutagenicity and DNA damage, and the results are summarized in the following table. Toxicity is expressed as a decrease in cell viability; mutagenicity is measured as the resistance to 6-thioguanine over a range of doses that renders 90C cells viable.