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目的探讨血清心肌酶谱活性检测在新生儿窒息的临床意义,指导治疗及预防。方法对61例窒息新生儿和34例正常的新生儿分别测定AST、LDH、CK、CK-MB4种心肌酶,并进行统计学处理。结果窒息新生儿心肌酶异常,并与窒息程度成正比,经统计学处理差异有统计学意义。结论心肌酶活性检测可作为围产期窒息后心肌损害的早期灵敏、特异性的重要指标,尤其是CKMB,临床上具有协助早期诊断和治疗重要实用价值。
Objective To investigate the clinical significance of serum myocardial enzyme activity in neonatal asphyxia and to guide the treatment and prevention. Methods The myocardial enzymes of AST, LDH, CK and CK-MB were determined in 61 neonates with asphyxia and 34 normal neonates. Statistical analysis was carried out. Results Asphyxia neonatal myocardial enzyme abnormalities, and asphyxia is proportional to the statistical difference was statistically significant. Conclusions The detection of myocardial enzyme activity may be used as an early sensitive and specific indicator of myocardial damage after perinatal asphyxia. CKMB, in particular, is clinically valuable in assisting early diagnosis and treatment.