骨肉瘤(osteosarcoma)是除浆细胞瘤以外最常见的恶性肿瘤,儿童骨肉瘤常采用保肢手术治疗,单纯截肢治疗约80%的患者因术后6～12个月发生早期血行转移或肺部转移而死亡。近20年以来由于化疗技术的应用和改进,儿童骨肉瘤特别是EnnckingⅡB期患者保肢生存率大幅度提高。早期诊断、? Osteosarcoma (osteosarcoma) is the most common malignancy except plasma cell tumor, osteosarcoma often used limb salvage surgery in children, simple amputation treatment of about 80% of patients after 6 to 12 months of early hematogenous metastasis or lung Transfer and die. In the past 20 years, due to the application and improvement of chemotherapy, the salvage rate of limb salvage in children with osteosarcoma, especially EnnckingⅡB, has been greatly improved. Early diagnosis,?