论文部分内容阅读
5例银屑病患者服用乙双吗啉治疗后,都发生了急性早幼粒细胞白血病(APL)。其骨髓细胞染色体研究,均揭示特征性的t(15;17)易位。据此,作者认为,染色体畸变是乙双吗啉引起治疗相关性白血病的主要原因。
Acute promyelocytic leukemia (APL) occurred in all 5 patients with psoriasis who received betamorphine. Their bone marrow cell chromosomes revealed the characteristic t (15; 17) translocation. Accordingly, the author believes that chromosomal aberration is the main cause of B-morphine-induced treatment-related leukemia.