原发性十二指肠癌相当少见,国内外文献报道较少,确切发病率难以统计。本文报告一例,并结合文献复习,略加讨论。病例介绍患者女,43岁。因食欲不振,恶心乏力,厌油腻一个月,伴全身黄染廿余天入院。病后十余天自觉全身出现黄染,大便呈浅灰色,便中带不消化残渣。尿变黄。诊为肝炎治疗无效,于1985年7月15日入院治疗。入院后查体:神志清,慢性病容,面色灰黄无 Primary duodenal cancer is rare, with few reports at home and abroad, and the exact incidence is difficult to count. This article reports an example, and combined with review of the literature, a little discussion. Case Description Female patient, 43 years old. Due to lack of appetite, nausea, fatigue, tired of greasy for a month, with the body yellow dye Yin Yu Tian admitted. After more than ten days of illness, the body appeared jaundically, and the stools were light gray, with indigestible debris. Urine becomes yellow. The diagnosis of hepatitis was invalid and he was admitted to hospital on July 15, 1985. Physical examination after admission: clear mind, chronic disease, pale complexion