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目的探讨过氧化氢、白细胞酯酶、唾液酸苷酶、β葡萄糖醛酸甘酶和凝固酶五项联合测定法应用于细菌性阴道病(BV)的诊断价值。方法阴道分泌物样本来自于我院妇科患者800例,检测方法为常规盐水法检验和五项联合测定法检验。结果800例受试者结合两种方法共检出BV患病者558例(69.75%)。以共同检出的558例患者为标准,五项联合测定法的检出率为45.16%,明显高于常规盐水法30.11%;漏诊率54.84%,明显低于常规盐水法69.89%,组间差异显著(P<0.05)。结论五项联合测定法应用于BV诊断较常规盐水法检出率更高,联合两种方法共同检测可获得更好效果,建议临床采纳。
Objective To investigate the diagnostic value of the combination of hydrogen peroxide, leukocyte esterase, neuraminidase, β-glucuronidase and coagulase in the diagnosis of bacterial vaginosis (BV). Methods Vaginal discharge samples from our hospital gynecological patients in 800 cases, the test method for routine saline test and five joint test. Results A total of 558 patients (69.75%) with BV were detected by 800 subjects combined with the two methods. The detection rate of 558 patients was 45.16%, which was significantly higher than that of routine saline method (30.11%). The misdiagnosis rate was 54.84%, which was significantly lower than 69.89% of routine saline method. The differences among groups Significant (P <0.05). Conclusions The five combined assays are more effective than conventional saline in the diagnosis of BV. The combined detection of the two methods can achieve better results and is recommended for clinical use.