论文部分内容阅读
目的调查分析一起航空器聚集性甲型H1N1流感疫情的流行病学特征,探讨与航空器有关的聚集性H1N1流感病例的发生原因以及可能的传播途径,为制定甲型H1N1流感防控策略提供依据。方法采用统一调查表经面对面调查结合现场调查,描述分析病例发病过程及流行病学特征,并采用病例对照研究相关因素。结果通过突发公共卫生疫情网报告了与本起航空器聚集性甲型H1N1流感疫情报告确诊病例8例,首例发病时间为2009年5月27日,其余病例发病时间集中在5月30日-6月1日;温哥华至香港航程期间戴口罩与发病具有统计学关联,温哥华至香港期间使用过7号卫生间(首例在该卫生间呕吐过),其OR达4.8(95%CI:0.5～56)。结论本次航空器聚集性病例流行病学曲线呈现点源暴露的特征;暴发可能来源于CX889航班,首例病例呕吐过的飞机尾部卫生间为可疑传播地点。在密闭空间中近距离接触传染源时佩戴口罩能有效预防被传染,对于实验室监测中采样的规范化、准确化,样本的保存运输,病毒核酸的实验室检测质量控制都是早期发现病例、防止二代病例出现的关键。
Objective To investigate and analyze the epidemiological characteristics of an H1N1 influenza A (H1N1) epidemic in aircraft and to explore the causes and possible routes of transmission of the H1N1 influenza associated with aircraft, so as to provide basis for the prevention and control strategy of Influenza A (H1N1). Methods The face-to-face survey combined with on-site investigation was conducted using a unified questionnaire to describe and analyze the pathogenesis and epidemiological characteristics of the cases and to use case-control studies. Results A total of 8 confirmed cases of Influenza A (H1N1) outbreaks were reported through the network of public health epidemic outbreaks. The first case was reported on May 27, 2009 and the rest cases were on May 30 - June 1; there was a statistically significant correlation between masks and incidence during the voyage from Vancouver to Hong Kong. In Vancouver to Hong Kong, toilet 7 (the first vomiting in the bathroom) was used, with an OR of 4.8 (95% CI: 0.5-56 ). Conclusions The epidemiological curve of aircraft aggregation shows a point-source exposure. The outbreak may originate from flight CX889. The vomited aircraft tail toilet in the first case is a suspected transmission site. In a confined space close contact with the source of infection when wearing a mask can effectively prevent infection, the sampling for the laboratory monitoring standardization, accuracy, preservation and transportation of samples, laboratory testing of nucleic acid quality control are detected in early cases, to prevent The second generation of cases the key.