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目的 :研究洗涤剂对小白鼠脂质过氧化的影响。方法 :给小白鼠分别饮用 1/ 4 0、 1/ 2 0、 1/ 10 L D50 的洗涤剂水溶液 30天 ,同时设对照组 ,测定血清中丙二醛 (MDA)含量和超氧化物歧化酶 (SOD)活性。结果 :两种洗涤剂可使小白鼠 MDA含量明显增加 ,SOD活性明显降低 ,与阴性对照组比较 P<0 .0 5。结论 :洗涤剂能使体内脂质过氧化含量显著增加 ,有可能对机体产生严重的损害
Objective: To study the effect of detergent on lipid peroxidation in mice. Methods: The mice were respectively dosed with 1/400, 1/10, 1/10 L D50 detergent solution for 30 days. At the same time, the rats in the control group were given serum MDA and superoxide dismutase (SOD) activity. Results: The two kinds of detergents could significantly increase MDA content and SOD activity in mice, P <0.05 compared with the negative control group. Conclusion: Detergent can significantly increase lipid peroxidation in the body, which may cause serious damage to the body