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目的探讨中西医结合治疗成人常复发性原发性肾病综合征（ＰＮＳ）的疗效。方法随机设置治疗组及对照组各４０例，前者用中西医结合治疗，后者单用西医治疗，二者间进行复发率、缓解期、不良反应比较。结果中西医结合组缓解后６个月、１２个月、４８个月的复发率分别为０、５．３％、１５．８％；平均缓解期为３５．７±３．８个月；对照组分别为１８．２％、２７．２％和３６．４％，平均缓解期为１２．５±３．１个月。中西医结合组各期复发率显著低于对照组（Ｐ＜０．０１）；缓解期显著长于对照组（Ｐ＜０．０１），且不良反应发生率低（Ｐ＜０．０１）。结论中西医结合治疗常复发性ＰＮＳ疗效优于单纯西医治疗。
Objective To investigate the curative effect of traditional Chinese medicine and western medicine on adult recurrent primary nephrotic syndrome (PNS). Methods A total of 40 cases were randomly divided into treatment group and control group. The former was treated with combination of TCM and Western medicine, while the latter was treated with Western medicine alone. The relapse rate, remission and adverse reactions were compared between the two groups. Results The recurrence rates of 6-month, 12-month and 48-month post-treatment in TCM-WM group were 0, 5.3% and 15.8% respectively; the average remission was 35.7 ± 3.8 months; Group were 18.2%, 27.2% and 36.4% respectively, the average remission was 12.5 ± 3.1 months. The recurrence rate of TCM-WM group was significantly lower than that of the control group (P <0.01). The remission period was significantly longer than that of the control group (P <0.01), and the incidence of adverse reactions was low (P <0.01). Conclusion The treatment of recurrent PNS with traditional Chinese and western medicine is superior to western medicine alone.