第一节胃和十二指肠溃疡胃、十二指肠溃疡是消化系统常见的慢性疾病,又叫溃疡病。其主要病变是胃或十二指肠的慢性溃疡。临床上有周期性上腹部疼痛、反酸、嗳气、呕吐等症状,易反复发作。患者多为青壮年,发病率男性高于女性。一、病因及发病机理在正常情况下,胃粘膜分泌的粘液在粘膜表面形成一层粘液膜。这种含有丰富类脂质的膜,可以防止胃酸透过上皮细胞进入粘膜层而损害组织。这就是胃粘膜的屏障机能。当这种屏障机能受到破坏时,胃酸则大量进入胃粘膜,发生组织自我消化,形成溃疡。此外,神经、内分泌机能失调,促进胃 Section stomach and duodenal ulcer stomach, duodenal ulcer is a common chronic disease of the digestive system, also known as ulcer disease. The main lesion is chronic ulcer of the stomach or duodenum. Periodically clinical upper abdominal pain, acid reflux, belching, vomiting and other symptoms, easy to recurrent. Mostly young patients, the incidence of men than women. First, the etiology and pathogenesis Under normal circumstances, gastric mucus secretion of mucus in the mucosal surface to form a layer of mucus membrane. This lipid-rich membrane, to prevent gastric acid through the epithelial cells into the mucosal layer and damage tissue. This is the gastric mucosal barrier function. When this barrier function is destroyed, gastric acid is a large number into the gastric mucosa, tissue self-digestion, the formation of ulcers. In addition, nervous, endocrine dysfunction, promote stomach