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目的探讨临床偶然发现的垂体占位性病变的诊断和处理。方法系统分析1989~1997年34例CT和MRI偶然检出的垂体占位性病变的临床资料。结果29例有头痛等颅内病变临床表现,仅3例表现轻度内分泌检查异常。34例中微型病灶占26例(775%)。26例经蝶手术切除病变,其病理诊断为:8例无功能大腺瘤,7例微腺瘤,5例垂体增生,6例Rathke囊肿。随诊23例无病变复发。结论重视对慢性头痛患者行CT和MRI检查。对大于15cm或10~1.5cm随诊期有病变增大证据者主张经蝶手术切除。而10cm以下的病变应定期随诊
Objective To explore the diagnosis and treatment of accidentally discovered pituitary space-occupying lesions. Methods The clinical data of 34 cases of accidental pituitary lesions detected by CT and MRI were systematically analyzed from 1989 to 1997. Results There were 29 cases with clinical manifestations of headache and other intracranial lesions, and only 3 cases showed mild endocrine abnormalities. Among the 34 cases, 26 cases (77.5%) were micro-lesions. Twenty-six cases were treated by transsphenoidal surgery. The pathological diagnosis was: 8 cases of non-functioning large adenomas, 7 cases of microadenomas, 5 cases of pituitary hyperplasia, and 6 cases of Rathke cysts. Followed up in 23 cases without disease recurrence. Conclusion The importance of CT and MRI in chronic headache patients was examined. For patients with evidence of lesions larger than 15cm or 10~1.5cm at the time of the follow-up examination, they should undergo transsphenoidal surgery. The lesions below 10cm should be regularly followed up