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目的 探讨老年 2型糖尿病微量白蛋白尿与血压、体重指数、高胰岛素血症以及胰岛素抵抗的关系。方法 按 WHO标准确诊的 2型糖尿病 57例全部在入院第一周内测定 2 4小时尿白蛋白排泄率 (2 4小时 UAE)。同时测血压以及血 BUN、CR、FBS、血浆空腹胰岛素 ,计算体重指数和胰岛素敏感性指数。结果 老年 2型糖尿病伴有早期糖尿病肾病的患者平均收缩压、体重指数及空腹血浆胰岛素均有显著增高 ,而胰岛素敏感性指数就有所下降。结论 为了防止老年人糖尿病慢性并发症的发生和发展 ,应尽早防治胰岛素抵抗 ,控制血压 ,合理控制饮食和运动 ,可提高胰岛素敏感性及反应性 ,可降低老年人糖尿病肾病以及心血管疾病的发生率和死亡率
Objective To investigate the relationship between microalbuminuria and blood pressure, body mass index, hyperinsulinemia and insulin resistance in type 2 diabetes mellitus in the elderly. Methods Fifty-seven patients with type 2 diabetes who were diagnosed according to WHO criteria were all given 2-4 hours urinary albumin excretion rate (24 hours UAE) within the first week of admission. At the same time, blood pressure and blood BUN, CR, FBS, fasting plasma insulin, body mass index and insulin sensitivity index were calculated. Results The average systolic blood pressure, body mass index and fasting plasma insulin in elderly type 2 diabetic patients with early diabetic nephropathy were significantly increased, while the insulin sensitivity index decreased. Conclusion In order to prevent the occurrence and development of chronic complications of diabetes in the elderly, insulin resistance, blood pressure control, diet and exercise control should be controlled as soon as possible to improve insulin sensitivity and reactivity and reduce diabetic nephropathy and cardiovascular disease in the elderly Rate and mortality