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近年来,有些学者试从外周血液的中性粒细胞之核突变化来寻找早期发现恶性肿瘤的实验诊断价值,认为中性粒细胞的核突变化对恶性肿瘤的发现有一定参考意义,可用于恶性肿瘤的诊断,但意见尚不一致.为此,我们于1976年开始对恶性肿瘤、其它疾病以及正常人共280例进行了核突的检查,以验证其临床的实用价值. 检查对象将280例分为三个组: 一、恶性肿瘤组:64例(63例系未经治疗的新病例,1例为术后复发转移者),男42人,女22人.各种恶性肿瘤均分别经X射线、脱落细胞学或病理学检查确诊(见表1).
In recent years, some scholars try to find out the value of experimental diagnosis of early detection of malignant neoplasm from the peripheral blood of neutrophils. We think that the neutrophil nuclear mutation has some reference to the detection of malignant tumors and can be used in Malignant tumor diagnosis, but the opinion is not consistent.To this end, we began in 1976, malignant tumors, other diseases and normal people a total of 280 cases of nuclear sudden check in order to verify its clinical value.Check the object will be 280 cases Divided into three groups: one, malignant tumor group: 64 cases (63 cases of untreated cases, one case of recurrence and metastasis), 42 males and 22 females.All malignant tumors were X-ray, cytology or pathological examination confirmed (see Table 1).