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目的观察超声引导下穿刺注射无水乙醇联合米非司酮治疗围绝经期子宫内膜异位症的临床疗效。方法 148例围绝经期子宫内膜异位症患者随机分为观察组和对照组,各74例。对照组给予超声引导下穿刺注射无水乙醇治疗;观察组在对照组的基础上增加口服米非司酮治疗。观察记录比较两组患者临床疗效情况,观察周期为3个月。结果对照组治愈12例,有效35例,总有效率63.5%,观察组治愈17例,有效42例,总有效率79.7%,观察组总有效率高于对照组,差异具有统计学意义(P<0.05)。结论超声引导下穿刺注射无水乙醇联合米非司酮治疗围绝经期子宫内膜异位症的临床疗效显著,并发症较少,提高了患者及患者家属的临床满意度。
Objective To observe the clinical efficacy of ultrasound guided percutaneous ethanol injection combined with mifepristone in the treatment of perimenopausal endometriosis. Methods 148 cases of menopausal endometriosis patients were randomly divided into observation group and control group, 74 cases in each. The control group was given ultrasound-guided puncture and injection of absolute alcohol. The observation group was given oral mifepristone on the basis of the control group. Observation records compared the clinical efficacy of two groups of patients, the observation period of 3 months. Results In the control group, 12 cases were cured, 35 cases were effective and the total effective rate was 63.5%. In the observation group, 17 cases were cured, 42 cases were effective and the total effective rate was 79.7%. The total effective rate in the observation group was higher than that in the control group (P <0.05). Conclusion Ultrasound-guided puncture injection of ethanol combined with mifepristone in the treatment of menopausal endometriosis has significant clinical efficacy, fewer complications, and improve the clinical satisfaction of patients and their families.