论文部分内容阅读
一、建立了动物脏器、组织中有机氯农药微量测定方法,样品用量0.1克,回收试验结果较为满意。二、全血中六六六异构体动态观察结果表明,血中丙体六六六含量与饲料中丙体六六六水平有关,但各剂量各阶段血中丙体六六六水平没有什么变化。血中丙体六六六浓度只反映剂量水平,不反映机体内蓄积程度。三、一年及两年三个月的喂养实验结果表明,饲料中丙体六六六水平与各脏器、组织中甲体六六六、丙体六六六蓄积量明显相关;特别值得重视的是低剂量组雄鼠肾脏丙体六六六高蓄积量与肾曲管上皮细胞病变关系。雌鼠肾脂中六六六异构体浓度与体脂中浓度处于同一水平,而雄鼠肾脂中甲体六六六、丙体六六六蓄积量比体脂中的浓度高得多,表现出雄鼠肾脏高蓄积六六六的特异性。
First, the establishment of animal organs, tissue micro-determination of organochlorine pesticides, the sample amount of 0.1 grams, the recovery test results are more satisfied. Second, the whole blood in the six six isomers dynamic observation results show that the blood C and B hexose content in the feed C hexamer six levels, but at all doses of blood C66 level of blood nothing Variety. Blood C66 concentration only reflects the dose level, does not reflect the degree of accumulation in the body. Three, one and two years of three months of feeding experiment results show that feed C and B hexagonal levels and viscera, tissue A and B six six, C is significantly related to the volume of BHC; in particular worthy of attention The low dose group male rat kidney C666 volume and renal tubule epithelial cell lesion relationship. The concentration of BHC in isoforms of female rat kidney fat was at the same level as that of body fat, while the accumulation of BHC and C66 in male kidney fat was much higher than that in body fat, Showed the high specificity of male rat kidney accumulation BHC.