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血清甲胎蛋白(AFP)的检测,对原发性肝癌的诊断具有较高的特异性和价值。近年来放射免疫法的推广应用,灵敏度较高,阳性率可达90%左右。国内用以普查上百万人,发现了一批无任何症状与体征的早期肝癌病人,为肝癌的早期诊断和早期治疗创造了条件。但也存在假阴性和假阳性,如不注意鉴别,很易误诊或漏诊。因此,必须正确理解和分析判断AFP检测结果,才能提高确诊率。我科从1977年9月起,开展放射火箭电泳自显影法检测AFP,至81年5月底共检测1993例,现对资料完整、诊断明确的273例总结分析如下:
The detection of serum alpha-fetoprotein (AFP) has high specificity and value in the diagnosis of primary liver cancer. In recent years, the promotion and application of radioimmunoassay has a high sensitivity, and the positive rate can reach about 90%. Domestically, it has used census for millions of people and found a group of early-stage liver cancer patients without any symptoms or signs, which has created conditions for the early diagnosis and early treatment of liver cancer. However, there are false negatives and false positives. If you do not pay attention to identification, it is easy to misdiagnose or missed diagnosis. Therefore, we must correctly understand and analyze the AFP test results in order to improve the diagnosis rate. Since September 1977, our department has conducted AFP by autoradiography of radioactive rocket electrophoresis, and it has detected a total of 1993 cases by the end of May of the year. The 273 cases with complete data and clear diagnosis are summarized as follows: