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可复性输精管经皮注射栓堵节育法过去一直以聚氨基甲酸乙酯弹性体(MPU-01)为栓堵材料,1986年又改用硅橡胶(LS-02)栓堵剂,经动物实验和临床观察,也具有良好的效果。方法和结果一、动物实验:①抗生育有效性试验:选体重为2.0～3.2kg有生育能力的健康雄性家兔20只进行输精管栓堵。栓堵2月后与健康有生育能力的雌性家兔配对合笼饲养4个月,观察其生育情况。观察结果无一只受孕,抗生育有效率达100％。。②栓子移动试验:于20只雄性家兔输精管内注入0.1～0.29ml LS-02栓堵剂,用黑丝线标记栓子位置,经4～8个月后分批剖腹观察栓子在输精管内的移动情况。观察结果表明,栓子移动与栓堵剂量有关,当注射剂量小于0.16ml时栓子有移动;剂量为0.16ml或以上时栓子无移动;当剂量达0.29ml
Refractory vasectomy percutaneous injection plug and socket birth control method in the past has been to polyurethane elastomer (MPU-01) as plugging material, in 1986 and the use of silicone rubber (LS-02) plugging agent, the animal experiments And clinical observation, also has good results. Methods and Results 1. Animal experiment: ① Anti-fertility effectiveness test: 20 healthy male rabbits with fertility of 2.0 ~ 3.2kg were selected for vasectomy. Plug and plug in February with healthy fertile female rabbits mating cage feeding for 4 months to observe the fertility. No pregnancy test results, anti-fertility rate of 100%. . ② emboli migration test: In 20 male rabbit vas deferens injected with 0.1 ~ 0.29ml LS-02 plugging agent, marking the embolus with black thread position, after 4 to 8 months after the laparotomy observed emboli in the vas deferens Mobile situation. Observations showed that the embolus movement and embolization dose related, when the injection dose is less than 0.16ml emboli move; dose of 0.16ml or more when the emboli no movement; when the dose of 0.29ml