目的 确定肿瘤组织起源，鉴别肿瘤良恶性，指导临床治疗及预后。方法 利用抗原、抗体特异性结合原理，在组织和细胞中进行抗原、抗体准确定性、定位的检测。结果 免疫组化提高了病理诊断准确性。结论 免疫组化在肿瘤的基础和临床研究中发挥着重要作用，尤其是对肿瘤的诊断、鉴别诊断、病因及发病机理的研究提供了强有力的手段。 Objective To determine the origin of tumor tissue, identify benign and malignant tumors, and guide clinical treatment and prognosis. Methods The principle of antigen and antibody specific binding was used to detect antigen and antibody quasi-determinism and localization in tissues and cells. Results Immunohistochemistry improved the accuracy of pathological diagnosis. Conclusion Immunohistochemistry plays an important role in the basic and clinical research of tumors, especially for the diagnosis, differential diagnosis, etiology and pathogenesis of tumors.