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目的：探讨乳腺癌中微血管数与预后因素淋巴结状态、ｐＳ２的关系。方法：用ＬＳＡＢ法检测浸润性乳腺癌（ＩＢＣ）中的微血管数（ＭＶＣ）和ｐＳ２表达。结果：在７６例ＩＢＣ中ＭＶＣ的均数是５７．８２±２２．２２；淋巴结阳性５２例中有远处转移２３例，无远处转移２９例，ＭＶＣ分别为６８．０２±２０．１２与５５．１８±１９．０８，差异有显著性（Ｐ＜０．０５）。腋淋巴结阴性２４例中，有远处转移９例，无远处转移１５例，ＭＶＣ分别为７０．７７±１１．１１与４２．６２±２３．５４，差异有显著性（Ｐ＜０．０１）。原发癌ｐＳ２阳性与阴性的病例，ＭＶＣ分别为５６．７５±１９．０６与６７．０８±２０．３３，差异有显著性（Ｐ＜０．０５）。结论：ＭＶＣ可作为乳腺癌一项预后指标，无论腋淋巴结阳性或阴性，原发癌ＭＶＣ越高越易形成远处转移；ＭＶＣ与ｐＳ２表达呈负相关
Objective: To investigate the relationship between the number of microvessel and the prognosis of lymph node status and pS2 in breast cancer. Methods: Microvessel count (MVC) and pS2 expression in invasive breast cancer (IBC) were detected by LSAB. Results: The average number of MVC in 76 cases of IBC was 57.82 ± 22.22. Of the 52 cases with lymph node metastasis, 23 cases had distant metastasis, 29 cases had no distant metastasis, and the MVC were 68.02 ± 20.12 and 55.18 ± 19.08, the difference was significant (P <0.05). Among the 24 cases with negative axillary lymph node metastasis, there were 9 distant metastasis, 15 distant metastasis, MVC 70.77 ± 11.11 and 42.62 ± 23.54 respectively (P <0.01) ). The positive and negative pS2 cases of primary cancer, MVC were 56.75 ± 19.06 and 67.08 ± 20.33, the difference was significant (P <0.05). Conclusions: MVC can be used as a prognostic indicator of breast cancer. No matter axillary lymph node is positive or negative, the higher the MVC of primary cancer, the easier it is to form distant metastasis. The negative correlation between MVC and pS2 expression