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为进一步探讨胆汁成份异常、胆囊动力学变化和胆囊结石形成之间的内在联系，对家兔胆囊结石动物模型进行了胆囊动力学研究。结果显示：除胆汁成份异常外，胆囊动力学变化参与了胆囊结石形成。消炎痛能减少胆汁粘蛋白含量抑制胆固醇成核过程而防止胆囊结石形成；而红霉素能通过促进胆囊收缩同时减少胆汁粘蛋白含量和促进胆囊排空，从而更有效地防止胆囊结石形成。提示：改善致石胆汁引起的胆囊动力学变化较改变胆汁成分更有利于防止胆囊结石形成。
To further explore the bile component abnormalities, gallbladder dynamics and gallbladder stone formation between the intrinsic link between the animal model of gallbladder stones gallbladder dynamics studies. The results showed that: in addition to abnormal bile composition, gallbladder dynamics involved in the formation of gallstone. Indomethacin can reduce bile mucin content and inhibit the process of cholesterol nucleation to prevent the formation of gallstones; and erythromycin can promote gallbladder contraction while reducing bile mucin content and promote gallbladder emptying, which is more effective in preventing gallstone formation. Tip: to improve the gallbladder caused gallbladder kinetic changes than the change of bile composition is more conducive to prevent gallstone formation.