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用差示扫描量热法(DSC)筛选确定双炔失碳酯与PVP,按1:7~1:9比例以溶剂法制得共沉淀物,其中已不存在双炔失碳酯晶体。用X射线衍射法研究了1:8共沉淀物,证明无双炔失碳酯的晶体衍射峰。经溶出速率测定,结果20分钟的药物溶出度1:8共沉淀物
An anordrin and PVP were identified by differential scanning calorimetry (DSC). Coprecipitates were obtained by solvate at a ratio of 1: 7 to 1: 9, and no crystals of anordrin were present. The 1: 8 coprecipitates were investigated by X-ray diffraction and the crystal diffraction peaks of the anomalins were proved. The dissolution rate determined that the 20 minute drug dissolution 1: 8 coprecipitate