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将132例功能性消比不良(FD)患者随机分成两组,均用西沙必利、阿莫西林治疗,治疗组加用多虑平,疗程4周。结果总有效率,治疗组91.7%,对照组66.7%(P<0.01)。提示FD的发病可能有神经机制参与,小剂量抗抑郁剂与胃肠动力药、抗HP药联用可增加疗效。
132 patients with functional dyspepsia (FD) were randomly divided into two groups, both with cisapride, amoxicillin treatment, the treatment group with doxepin, treatment for 4 weeks. The total effective rate was 91.7% in the treatment group and 66.7% in the control group (P <0.01). Tip FD pathogenesis may have neurological mechanisms involved in small doses of antidepressants and gastrointestinal motility drugs, anti-HP drug combination can increase efficacy.