难治性肾病综合征 (ＲＮＳ)临床上治疗非常棘手 ,患者常常处于蛋白质营养不良状态 ,不合理的饮食及营养治疗不但会加重肾功能的损害 ,而且还能诱发或加重肾病综合征的并发症。笔者就低蛋白饮食加α -酮酸治疗ＲＮＳ的疗效进行了观察。１．１对象２０例ＲＮＳ患者 ,男性１４例 , Clinic treatment of refractory nephrotic syndrome (RNS) is very tricky. Patients often suffer from protein malnutrition. Unreasonable diet and nutritional therapy not only aggravate renal dysfunction, but also induce or aggravate the complications of nephrotic syndrome . The author of low protein diet plus α - keto acid treatment of RNS were observed. 1.1 object 20 cases of RNS patients, 14 males,