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作者应用终点法检测了 12 2例原发性肝癌和其他肝病患者血清α—L—岩藻糖苷酶 (AFU)水平 ,并探讨了其对原发性肝癌的诊断意义 ,发现原发性肝癌患者血清AFU浓度显著高于其它疾病组和对照组 (P <0 0 1)。并得出AFU对原发性肝癌的诊断敏感度为 77 9% ,特异性为 97 6 % ,准确度为 89 1% ,且AFU水平与甲胎蛋白 (AFP)浓度之间无相关性的结论。因此血清AFU对原发性肝癌的诊断及鉴别有一定价值。尤其对AFP阴性肝癌有更重要意义。
The authors used the endpoint method to detect serum α-L-fucosidase (AFU) levels in 122 patients with primary liver cancer and other liver diseases, and explored its significance for the diagnosis of primary liver cancer and found that patients with primary liver cancer Serum AFU concentrations were significantly higher than other disease groups and controls (P < 0 01). It was concluded that AFU had a diagnostic sensitivity of 77 9%, specificity of 976 %, accuracy of 89 1%, and no correlation between AFU levels and alpha fetoprotein (AFP) concentrations. . Therefore serum AFU has a certain value for the diagnosis and identification of primary liver cancer. Especially for AFP-negative liver cancer is more important.