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用间接酶联免疫吸附实验（ＥＬＩＳＡ）测定１３４例病毒性心肌炎患儿的柯萨奇病毒Ｂ（ＣＶＢ）特异性ＩｇＭ。其中阳性５８例总阳性率为４３．３５％，以正常人血清３０例做对照，仅１例为阳性，占３．２％。两者比较（χ２＝６．４０７５，Ｐ＜０．０５），有显著差异性。病程早期（半月内）阳性率较高，病程超过８周者２７例，阳性检出率４０．３％，阳性检出机会仍然较多。提示ＣＶＢ在病毒感染的心肌炎中是主要的病原。临床检测特异性ＩｇＭ不仅有早期病原学诊断意义，并能观察重复感染及迁延不愈的动态。
Coxsackievirus B (CVB) -specific IgM was measured in 134 children with viral myocarditis by indirect enzyme-linked immunosorbent assay (ELISA). Among them, the positive rate of 58 cases was 43.35%, compared with 30 cases of normal serum, only 1 case was positive, accounting for 3.2%. There was significant difference between the two groups (χ2 = 6.4075, P <0.05). Early stage of disease (within half a month) positive rate, duration of more than 8 weeks in 27 cases, the positive detection rate of 40.3%, positive detection opportunities are still more. Tip CVB in viral myocarditis is the main pathogen. Clinical detection of specific IgM not only has the significance of early etiological diagnosis, and can observe the dynamic of repeated infections and delayed healing.