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目的对乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和艾滋病病毒(HIV)经血传播的残余风险进行评估,为输血安全与血液监测提供理论依据。方法以深圳市2001-2004年献血员的病毒检测筛查数据为基础,采用现有的模型对HBV、HCV和HIV经血传播的残余风险进行评估。结果2001-2004年深圳经血传播HBV、HCV、HIV的残余风险分别为1∶7 698,1∶34 128和1∶1 373 064即每百万单位血有130.0单位感染HBV,每百万单位血有29.0单位感染HCV和每百万单位血有0.73单位感染HIV。结论与西方国家情况相比,深圳经血传播HBV、HCV的残余风除比较高,但经血传播HIV的残余风险与西方国家具有可比性。
Objective To evaluate the residual risk of blood transmission of Hepatitis B virus (HBV), Hepatitis C virus (HCV) and HIV (Human immunodeficiency virus) and provide a theoretical basis for blood transfusion safety and blood monitoring. Methods Based on the screening data of blood donors from 2001 to 2004 in Shenzhen City, the residual risk of blood transfusion of HBV, HCV and HIV was evaluated using the existing models. Results The residual risks of transmitting HBV, HCV and HIV in Shenzhen during 2001-2004 were respectively 1: 7 698, 1: 34 128 and 1: 1 373 064, ie 130.0 units per million unit of blood were infected with HBV, There were 29.0 units infected with HCV and 0.73 units infected with HIV per million units of blood. Conclusion Compared with the western countries, the residual winds of HBV and HCV transmitted by menstrual blood in Shenzhen are relatively high, but the residual risk of blood transmitted by HIV is comparable with that of western countries.