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目的分析IHA检测疫区人群血吸虫特异性抗体水平及其动态变化。方法采用IHA检测华容区2002～2011年间不同地域、不同年龄人群血吸虫特异性抗体水平,进行分析。结果鄂州市华容区各乡镇2011年人群血吸虫特异抗体IHA检测阳性率与2002年比较,平均下降42.31%,其中2002各年龄段人群2011年血吸虫特异抗体IHA检测阳性构成比与2002年比较,36岁以下年龄组均有所下降,其中6～龄组从11.67%降至0.93%,下降91.99%,26～龄组降幅为69.41%,16～龄组下降66.36%,36～龄组人群IHA阳性构成比差异无统计学意义(P>0.05);46～及以上年龄组人群IHA检测阳性构成比则均呈上升趋势,三个年龄组总构成比由2002年的30.00%上升至2011年的67.29%,各年度平均涨幅为12.42%。结论鄂州市华容区各地域人群血吸虫特异性抗体IHA检测阳性水平已普遍下降,从年龄分组来看,中老年人群血吸虫特异性抗体水平高于其他年龄人群,是今后血吸虫病防控工作的重点目标人群。
Objective To analyze the levels and dynamic changes of specific antibodies against Schistosoma japonicum in IAPs. Methods The IHA was used to detect the levels of schistosoma japonicum specific antibodies in Huarong district from 2002 to 2011 in different regions and different ages. Results In 2011, the positive rate of IHA detection of schistosoma japonicum specific antibodies in each township of Ezhou Huarong district dropped by an average of 42.31% compared with that in 2002. The positive constituent ratio of IHA in schistosoma japonicum in 2011 among all age groups in 2011 was 36 years The following age groups decreased, of which the 6 ~ age group decreased from 11.67% to 0.93%, decreased 91.99%, 26 ~ age group decreased 69.41%, 16 ~ age group decreased 66.36%, 36 ~ age group IHA positive constitution (P> 0.05). The positive ratio of IHA in 46-year-old and above-age groups showed an upward trend, the total composition ratio of three age groups increased from 30.00% in 2002 to 67.29% in 2011, , The average annual increase of 12.42%. Conclusion The positive IHA levels of schistosome-specific antibodies in various regions of Huarong District of Ezhou City have generally declined. From the perspective of age group, the levels of schistosome-specific antibodies in middle-aged and elderly population are higher than those in other age groups, which is the key target of prevention and control of schistosomiasis in the future crowd.