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母胎界面细胞因子相对平衡对正常妊娠的维持有重要作用。近年来研究发现孕妇外周血Th1/Th2细胞因子失衡与妊娠期高血压疾病的发生有密切关系。但并非作为孤立的因素而是与多因子共同推动HDCP的发展,并在其中起着关键的调控作用。因此纠正Th1/Th2失衡可能为HDCP预防和治疗提供新的思路。
The relative balance of maternal-fetal interface cytokines plays an important role in the maintenance of normal pregnancy. In recent years, studies have found that the imbalance of Th1 / Th2 cytokines in peripheral blood of pregnant women is closely related to the occurrence of hypertensive disorder complicating pregnancy. But not as an isolated factor but with the multi-factor together to promote the development of HDCP, which plays a key regulatory role. Therefore, correcting the imbalance of Th1 / Th2 may provide new ideas for the prevention and treatment of HDCP.