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目的调查微量白蛋白尿与代谢综合征(MS)各组分的关系。方法采用横断面流行病学调查20~79岁畲族人群,采用统一调查表记录畲族受试者基本信息,测定其血压、血糖、血脂、腰围、体重等情况。采用Micral-Test试纸半定量比色法筛查尿微量白蛋白。结果纳入统计学分析共2473例,MS及尿蛋白发病率各为17.8%、15.8%。随着代谢异常数目的增加,微量白蛋白尿患病率明显增加(P<0.001)。年龄、性别调整后,与MS组相比,MS组发生微量白蛋白尿的风险比值为3.77(95%CI,2.56~5.55)。多元回归分析提示高血糖、高血压、高三酰甘油血症是微量白蛋白尿的独立危险因素。结论微量白蛋白尿与MS及其组分密切相关,与高血糖、高血压、高三酰甘油血症独立相关。
Objective To investigate the relationship between microalbuminuria and various components of metabolic syndrome (MS). Methods A cross-sectional epidemiological study of She population aged 20-79 years was conducted. The basic information of She subjects was recorded by a unified questionnaire and the blood pressure, blood glucose, blood lipid, waist circumference and body weight were measured. Urine microalbumin was screened by semi-quantitative Micrac-Test strip. Results A total of 2473 cases were included in the statistical analysis. The incidences of MS and urinary protein were 17.8% and 15.8% respectively. As the number of metabolic abnormalities increased, the prevalence of microalbuminuria was significantly increased (P <0.001). After adjusting for age and sex, the risk ratio of microalbuminuria in MS group was 3.77 (95% CI, 2.56-5.55) compared with MS group. Multivariate regression analysis suggested that hyperglycemia, hypertension and hypertriglyceridemia were independent risk factors of microalbuminuria. Conclusion Microalbuminuria is closely related to MS and its components, and is independently related to hyperglycemia, hypertension and hypertriglyceridemia.